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Oxidative Stress and Sperm DNA Fragmentation Explained

Oxidative Stress and Sperm DNA Fragmentation Explained

by Dr. Leila Fazlicic, D.Ac, L.Ac | Sep 10, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research The short answer: Oxidative stress and sperm DNA fragmentation are two ends of the same process: when reactive oxygen species (ROS) outnumber the antioxidant...
The 2025 Sperm DNA Fragmentation Guidelines, Translated for Couples

The 2025 Sperm DNA Fragmentation Guidelines, Translated for Couples

by Dr. Leila Fazlicic, D.Ac, L.Ac | Aug 29, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research The short answer: In 2025, 52 experts from the Global Andrology Forum published the first comprehensive sperm DNA fragmentation guidelines — 24 evidence-graded...
Sperm DNA Fragmentation Testing: Cost, How to Get It, and What Your DFI Number Means

Sperm DNA Fragmentation Testing: Cost, How to Get It, and What Your DFI Number Means

by Dr. Leila Fazlicic, D.Ac, L.Ac | Aug 5, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research Short answer: A sperm DNA fragmentation test — often reported as a DFI, or DNA Fragmentation Index — measures the percentage of a man’s sperm carrying...
When IVF Keeps Failing: Why It’s Time to Look Beyond the “Female Factor” and Consider His Sperm DNA

When IVF Keeps Failing: Why It’s Time to Look Beyond the “Female Factor” and Consider His Sperm DNA

by Dr. Leila Fazlicic, D.Ac, L.Ac | Jul 14, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research The short answer: sperm DNA fragmentation (SDF) is damage to the genetic material inside sperm that a standard semen analysis never measures — a man can have...
What Actually Lowers Sperm DNA Fragmentation in 74 Days

What Actually Lowers Sperm DNA Fragmentation in 74 Days

by Dr. Leila Fazlicic, D.Ac, L.Ac | Jun 13, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research The short answer: the five inputs with the strongest evidence for lowering sperm DNA fragmentation within one ~74-day sperm production cycle are deep,...
Normal Semen Analysis, Failed Cycle: The One Test Nobody Ordered

Normal Semen Analysis, Failed Cycle: The One Test Nobody Ordered

by Dr. Leila Fazlicic, D.Ac, L.Ac | Jun 13, 2026 | Sperm DNA Fragmentation

Evidence-based · Written by Dr. Leila Fazlicic, D.Ac, L.Ac · All key claims cited to peer-reviewed research The short answer: a normal semen analysis does not rule out a male factor. It measures count, motility, and morphology — but not sperm DNA fragmentation (DFI),...

Recent Posts

  • Oxidative Stress and Sperm DNA Fragmentation Explained
  • How Stress Affects Fertility: One Alarm, Many Inputs
  • Antioxidants for Male Fertility: What the Expert Recommendations Actually Say (and Don’t)
  • After a Failed IVF Cycle: What to Do in the 90 Days Before You Try Again
  • The 2025 Sperm DNA Fragmentation Guidelines, Translated for Couples

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